Barriers to an early switch from intravenous to oral antibiotic therapy in hospitalized patients with community-acquired pneumonia

نویسندگان

  • M. F. Engel
  • F. Teding van Berkhout
چکیده

1. Department of Internal Medicine and Infectious Diseases, Utrecht University Medical Centre, the Netherlands. 2. Scientific Institute for Quality of Healthcare, Radboud University Medical Centre, the Netherlands. 3. Department of Pulmonary Diseases, Utrecht University Medical Centre, the Netherlands. 4. Department of Geriatric Diseases, Utrecht University Medical Centre, the Netherlands. 5. Department of Internal Medicine, Diakonessen Hospital, Utrecht, the Netherlands. 6. Department of Internal Medicine, Meander Medical Centre, Amersfoort, the Netherlands. 7. Department of Nephrology, VU University Medical Centre, Amsterdam, the Netherlands.

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Comparison of Early Intravenous to Oral Switch Amoxicillin/clavulanate with Parenteral Ceftriaxone in Treatment of Hospitalized Patients with Community Acquired Pneumonia

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Barriers to an early switch from intravenous to oral antibiotic therapy in hospitalised patients with CAP.

Do physicians apply an early-switch strategy (from intravenous to oral antibiotics) in clinically stable patients hospitalised with community-acquired pneumonia (CAP)? If not, why not? In a multicentre prospective cohort study, adult patients admitted for i.v. CAP treatment were included. On day 3 of antibiotic treatment, clinical stability was assessed and treating resident physicians were int...

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Switch therapy in hospitalized patients with community-acquired pneumonia: Tigecycline vs. Levofloxacin

BACKGROUND Switch therapy is a management approach combining early discontinuation of intravenous (IV) antibiotics, switch to oral antibiotics, and early hospital discharge. This analysis compares switch therapy using tigecycline versus levofloxacin in hospitalized patients with community-acquired pneumonia (CAP). METHODS A prospective, randomized, double-blind, Phase 3 clinical trial; patien...

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The pneumonia severity index predicts time to clinical stability in patients with community-acquired pneumonia.

SETTING A total of 33 hospitals in 13 countries in North America, Europe, Africa, Asia and Latin America. OBJECTIVE To investigate the relationship between the pneumonia severity index (PSI) and the time to clinical stability from intravenous to oral antibiotic therapy in hospitalized adult patients with community-acquired pneumonia (CAP). DESIGN An international, retrospective, observation...

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تاریخ انتشار 2012